This video game is similar to the previous, NFL Football '94 Starring Joe Montana, except in this version, there is no play by play commentary, the lineups of the football teams are updated to reflect the 1994 NFL season, and there are more plays for the player's football team to perform on offense and defense. Once again, Joe Montana appears on the title screen.

Despite the updated rosters, the game is notable in that it still had Deion Sanders as a member of the Atlanta Falcons instead of the San Francisco 49ers, with whom Sanders signed as a free agent during the offseason. The 49ers went on to win Super Bowl XXIX in Sanders' only season with the team before signing with the rival Dallas Cowboys the following offseason.

The game featured Free Agency, Create-A-Player (which allowed players to create a 21-year-old rookie and adjust his vital statistics), and varied in-game music.

The game was followed by similar releases, NFL '97 and NFL Prime Time '98.